Publications by authors named "C M Gupte"

Article Synopsis
  • The study reports the first successful in-vivo use of a new low-field MRI scanner that can rotate, applying the magic angle effect to better visualize collagen structures in knee ligaments and the meniscus.
  • The researchers developed a transverse field open magnet MRI system and conducted tests on healthy volunteers, focusing on the anterior cruciate ligament (ACL) and meniscus, capturing detailed images of collagen fibers.
  • The results demonstrated that this new method produced high-quality, in-vivo images comparable to traditional MRI used on excised specimens, indicating the potential for better imaging of joint injuries and diseases in a more accessible way.
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Article Synopsis
  • - The COVID-19 pandemic has significantly impacted healthcare, particularly in trauma and orthopedic care for children, leading to the necessity for improved management guidelines in future crises.
  • - A systematic review was conducted, analyzing published guidelines from English-speaking countries regarding pediatric trauma and orthopedics during the pandemic.
  • - The review identified 21 relevant guidelines from a search of multiple databases, emphasizing the need to adapt clinical practices to ensure effective pediatric care in similar future pandemics.
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Article Synopsis
  • More kids are getting knee injuries because they’re playing sports more and getting bigger.
  • To figure out what’s wrong, doctors need to ask about how the injury happened and check for pain or swelling.
  • If there are serious signs like broken bones or unusual pain, kids should see a specialist to get the right treatment!*
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Background: Brain bases and progression of methotrexate-associated neurotoxicity and cognitive disturbances remain unknown. We tested whether brain abnormalities worsen in proportion to intrathecal methotrexate(IT-MTX) doses.

Methods: In this prospective, longitudinal study, we recruited 19 patients with newly diagnosed acute lymphoblastic leukemia 4-to-20 years of age and 20 matched controls.

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