Publications by authors named "C M Gosden"
Article Synopsis
- - Atmospheric particulate matter (PM) is responsible for 3.7 million deaths annually and can harm all body organs, highlighting the critical relationship between air quality and health.
- - Over half of the global population lives in cities, raising concerns about PM emissions; however, knowledge about urban PM exposure is limited to data collected since the 1990s.
- - Researchers in Merseyside, England, reconstructed 200 years of air pollution records from urban pond sediments, revealing a shift from coarse soot emissions in the mid-20th century to finer combustion-derived PM post-1980, which reflects changes in urban development and has implications for understanding long-term pollution exposure.
Fossils, fish and tropical forests: prehistoric human adaptations on the island frontiers of Oceania.
Philos Trans R Soc Lond B Biol Sci
April 2022
Article Synopsis
- * Researchers used radiocarbon dating and stable isotope analysis on the earliest human remains from Near and Remote Oceania, finding the oldest fossil outside of mainland New Guinea dates to about 11,800 years ago.
- * The study reveals that early populations in the region relied heavily on resources from interior tropical forests, challenging the assumption that their diets were mainly coastal, thus broadening our understanding of their cultural practices and dietary habits.
Background: Dental calculus, calcified oral plaque biofilm, contains microbial and host biomolecules that can be used to study historic microbiome communities and host responses. Dental calculus does not typically accumulate as much today as historically, and clinical oral microbiome research studies focus primarily on living dental plaque biofilm. However, plaque and calculus reflect different conditions of the oral biofilm, and the differences in microbial characteristics between the sample types have not yet been systematically explored.
View Article and Find Full Text PDFAdvances in genomic and transcriptome sequencing are revealing the massive scale of previously unrecognised alterations occurring during neoplastic transformation. Breast cancers are genetically and phenotypically heterogeneous. Each of the three major subtypes [ERBB2 amplified, estrogen receptor (ESR)-positive and triple-negative] poses diagnostic and therapeutic challenges.
View Article and Find Full Text PDFAims: To assess the impact of continual major National Health Service reorganization on commissioning, organizational and delivery arrangements for secondary care diabetes services. To explore how consultant diabetologists and diabetes specialist nurses perceive the issues facing diabetes specialist services in 2011 and how these have changed in the preceding decade.
Methods: We used a longitudinal case study approach that combined quantitative and qualitative methods.