Publications by authors named "C M Frey"

Cell walls play essential roles in cell recognition, tissue adhesion, and wound response. In particular, pectins as cell-adhesive agents are expected to play a key role in the early stages of grafting. To test this premise, this study focused on examining the dynamics of the accumulation and degree of methyl-esterification of pectic polysaccharides at the graft junctions using tomato autografts as an experimental model.

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Background: Injury to the posterior vasculature is a potential complication in orthopaedic knee surgery that may be associated with variations in its anatomy, such as the type II-A2 variant, which places the anterior tibial artery (ATA) in closer proximity to the tibia. However, how close surgical instrumentation comes to injuring the ATA is not well described.

Purpose: To determine how the type II-A2 variant of the popliteal vasculature affects proximity of the ATA to instrumentation for orthopaedic knee procedures.

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Article Synopsis
  • Cutaneous lupus erythematosus (CLE) is a skin-related manifestation of lupus erythematosus, classified into subtypes (acute, subacute, chronic) based on clinical characteristics and lab findings.
  • Traditional treatments include topical corticosteroids and antimalarial drugs, but new immunomodulatory therapies, particularly Janus kinase (JAK) inhibitors, are emerging options.
  • The review highlights the importance of understanding the JAK/STAT signaling pathway in CLE management and calls for more research on the safety and effectiveness of JAK inhibitors for autoimmune disease treatment.
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Article Synopsis
  • The study focuses on assessing the impact of buprenorphine-naloxone on mortality and remission rates among patients with opioid use disorder (OUD), amidst rising opioid-related deaths in the U.S.
  • Using data from nearly 92 million medical records, the research compares outcomes between patients treated with buprenorphine-naloxone and a control group not receiving this treatment.
  • Findings indicate that patients on buprenorphine-naloxone experienced 34% fewer deaths and approximately 1.9 times higher remission rates compared to those who did not receive the medication.
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