Formulation Factors Affecting the Formation of Visible-Bubbles During the Reconstitution Process of Freeze-Dried Etanercept Formulations: Protein Concentration, Stabilizers, and Surfactants.

Freeze drying is one of the common methods to extend the long-term stability of biologicals. Biological products in solid form have the advantages of convenient transportation and stable long-term storage. However, long reconstitution time and extensive visible bubbles are frequently generated during the reconstitution process for many freeze-dried protein formulations, which can potentially affect the management efficiency of staff, patient compliance, and product quality.

Global impacts of land use on terrestrial carbon emissions since 1850.

Since the Industrial Revolution, significant changes in global land-use patterns have occurred, which have disrupted terrestrial carbon emissions. However, the disturbance processes, change trends, and distribution patterns are not clear. Therefore, the changes in terrestrial carbon emissions (E) caused by land-use change (LUC) since 1850 were analyzed in this study.

Bifunctional NiCo-CuO Nanostructures: A Promising Catalyst for Energy Conversion and Storage.

This investigation explores the potential of co-incorporating nickel (Ni) and cobalt (Co) into copper oxide (CuO) nanostructures for bifunctional electrochemical charge storage and oxygen evolution reactions (OER). A facile wet chemical synthesis method is employed to co-incorporate Ni and Co into CuO, yielding diverse nanostructured morphologies, including rods, spheres, and flake. The X-ray diffraction (XRD) and Raman analyses confirmed the formation of NiCo-CuO nanostructure, with minor phases of nickel oxide (NiO) and cobalt tetraoxide (CoO).

UV-Cured Robust and Transparent Double-Layer Membrane on Windows for Water Harvesting and Room Cooling.

The increasing demand for energy in cooling systems due to global warming presents a significant challenge. Conventional air-conditioning methods exacerbate climate change by contributing to heightened carbon emissions. Glass facades, renowned in modern architecture for their versatility and aesthetic appeal, inadvertently trap solar radiation, resulting in heat buildup and the greenhouse effect.

Efficacy of virtual reality balance training on rehabilitation outcomes following anterior cruciate ligament reconstruction: A systematic review and meta-analysis.

Objective: The objective of this systematic review and meta-analysis is to clarify the rehabilitation efficacy of virtual reality (VR) balance training after anterior cruciate ligament reconstruction (ACLR).

Methods: This meta-analysis was registered in PROSPERO with the registration number CRD42024520383. The electronic databases PubMed, Web of Science, Cochrane Library, MEDLINE, Embase, China National Knowledge Infrastructure, Chinese Biomedical Literature, China Science and Technology Journal Database, and Wanfang Digital Periodical database were systematically searched to identify eligible studies from their inception up to January 2024.