Publications by authors named "C M Dierikx"
Article Synopsis
- The study explores the relationship between antimicrobial use (AMU) in livestock and antimicrobial resistance (AMR) in human infections in the Netherlands from 2004 to 2020.
- It finds that while AMU in livestock is decreasing, AMR among human infections is still increasing, indicating that reducing livestock AMU alone may not effectively combat AMR in humans.
- The research highlights the need for further investigation into the genetic and evolutionary factors contributing to AMR, suggesting that a broader strategy may be needed to address this public health issue.
Association between antimicrobial usage in livestock and antimicrobial resistance in Escherichia coli isolates from human urinary tract infections in the Netherlands, 2009-2020.
J Antimicrob Chemother
October 2024
Background: In the last decade, veterinary antimicrobial usage (AMU) and antimicrobial resistance (AMR) among indicator bacteria in livestock have decreased substantially in the Netherlands. The extent to which this decrease has affected AMR levels among human infections remains unclear.
Objectives: To assess the association between AMU in livestock and AMR in Escherichia coli isolates from human urinary tract infections (UTIs).
Background: Antimicrobial use (AMU) in livestock contributes to antimicrobial resistance (AMR) among zoonotic pathogens, such as non-typhoid (NTS). Since 2009, the Netherlands has made substantial efforts to reduce AMU in livestock.
Objectives: To assess the association between AMU in livestock and AMR in NTS human isolates.
We investigated to what extent the consumption of raw or undercooked vegetables, fruits, and fresh herbs influences carriage rates of ESBL/pAmpC-producing and (ESBL-E/K) in the general population. We assessed long-term carriage and changes in ESBL-E/K prevalence over time, by comparing the results to findings in the same population 5 years earlier. Between July and December 2021, participants sent in two fecal samples and questionnaires, 3 months apart.
View Article and Find Full Text PDFObjectives: MRSA carrying the mecC gene (mecC-MRSA) have been found in humans and animals worldwide. A high carriage rate of mecC-MRSA has been described among hedgehogs in different countries. We performed genomic comparison of mecC-MRSA from hedgehogs and humans using next-generation sequencing (NGS) to investigate possible zoonotic transmission in the Netherlands.
View Article and Find Full Text PDF