Publications by authors named "C M Dickinson"
Article Synopsis
- * Elevated CO levels, nutrients, and temperatures lead to harmful algal blooms (HABs), which can negatively impact water quality, ecosystems, and public health due to the production of toxins.
- * The review discusses the dual role of algal blooms in carbon fixation and their complex metabolites, highlights advancements in understanding these structures, and examines strategies for managing and controlling HABs.
Article Synopsis
- Researchers used computer predictions to design antiviral compounds targeting specific proteins (Nsps) in the SARS-CoV-2 virus responsible for mRNA maturation and immune evasion.
- The compound Chromenephenylmethanone-1 (CPM-1), selected for its high specificity, was synthesized and tested, showing impressive results with 98.9% inhibition of the virus and no harmful effects on cells.
- This study highlights the effectiveness of computational modeling in discovering and developing new antiviral drugs against COVID-19.
Clinical Relevance: Refractive and ocular motor anomalies may be more prevalent among autistic adults without learning disabilities, compared to a non-autistic clinical population. In line with current guidance, optometrists should exclude these anomalies prior to prescribing tinted lenses.
Background: Autistic adults report various visual experiences with largely negative consequences on daily living.
Article Synopsis
- The study investigates how the chromatin and protein expressions of colonic epithelial cells differ between healthy individuals and patients with ulcerative colitis (UC), highlighting the role of epithelial dysfunction in UC pathology.
- Researchers sorted and analyzed epithelial cells from colon biopsies of healthy controls and UC patients to uncover these differences in proteome and chromatin accessibility.
- Results show significant protein elevation linked to inflammation in UC, with a notable reduction of the water channel aquaporin 8, indicating specific epigenetic mechanisms that influence protein expression in health vs. disease.
Purpose: This study measured the time course mV̇O 2 max following both maximal and submaximal exercise.
Methods: Healthy male and female participants were tested ( n = 12 maximal and n = 8 submaximal exercise). A NIRS device was placed on the left medial gastrocnemius.