Generic Elasticity of Thermal, Underconstrained Systems.

Athermal (i.e., zero-temperature) underconstrained systems are typically floppy, but they can be rigidified by the application of external strain, which is theoretically well understood.

Global prevalence and moderating factors of malnutrition in colorectal cancer survivors: A meta-analysis.

Purpose: This meta-analysis aims to estimate the global prevalence of severe, moderate, overall malnutrition and moderating factors of malnutrition in colorectal cancer (CRC) survivors.

Methods: A comprehensive search was conducted in Embase, CINAHL, Medline-OVID, PubMed, Scopus, and Web of Science from inception to February 8, 2024, without language, region, or publication date restrictions. A generalized linear mixed model and random-effects model were used to examine the pooled prevalence, and moderator analyses were implemented to investigate variations in the pooled prevalence.

Urban, formerly incarcerated, black, heterosexual men with substance use disorders: eligible for pre-exposure prophylaxis (PrEP) but unaware of their vulnerability to HIV acquisition.

Research on incarcerated men indicates low PrEP access even though HIV disproportionately affects them. Intersecting attributes - urban, incarcerated, Black, heterosexual men with substance use diagnoses (SUDs) - improves the odds of HIV transmission/acquisition. It is crucial to determine, among "key populations," who might be eligible to take PrEP.

Durvalumab, Tremelimumab, and Platinum Chemotherapy in Mutation-Positive NSCLC: An Open-Label Phase 2 Trial (ILLUMINATE).

Introduction: -mutant NSCLC is associated with low mutation burden and low levels of PD-L1 expression. We conducted a phase 2 trial to determine the efficacy of durvalumab, tremelimumab, and platinum-pemetrexed in mutant NSCLC after progression with EGFR tyrosine kinase inhibitors (TKIs).

Methods: Participants were treated with induction durvalumab, tremelimumab, and platinum-pemetrexed, followed by durvalumab-pemetrexed maintenance.

GaAs gradient metasurface for vortex beam emission with high deflection angles.

This study experimentally demonstrates metasurfaces capable of producing output emissions with deflection angles greater than 75 degrees. These metasurfaces are composed of high-aspect-ratio gallium arsenide (GaAs) nano-resonators on double-sided polished GaAs substrates, operating reflectively at a wavelength of 650 nm. Beyond deflecting the incident light beam, the metasurfaces are successfully shown to generate high-deflection-angle, doughnut-shaped emissions by incorporating vortex beam (VB) structured light with a topological charge of up to 8.