Publications by authors named "C M Bunke"

Background: Loneliness is a significant risk factor for both mental and physical health issues, including depression and increased mortality. Loneliness is reported at higher levels during life transitions, such as the transition to motherhood. Loneliness in mothers has far-reaching detrimental impacts on both mother and child, such as an increased risk of maternal depression and child abuse.

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Key Points: In our patients with FSGS, elevated proteinuria and progression to kidney failure (KF) were associated with a higher risk of cardiovascular disease/all-cause mortality events. In addition, elevated pre-KF proteinuria was associated with KF/all-cause mortality events. CKD stage, nephrotic syndrome, and cardiovascular disease event rates, as well as the incremental costs of these events, were high.

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Article Synopsis
  • A study on IgA nephropathy (IgAN) found that higher levels of proteinuria and progression to kidney failure (KF) significantly increased the risk of cardiovascular disease and mortality among patients.
  • The research analyzed data from adult patients with IgAN from 2007 to 2021, focusing on the relationship between protein levels and health outcomes using various statistical models.
  • Results indicated that patients with pre-KF status and high proteinuria were 1.8 times more likely to have cardiovascular events and over 2 times more likely to progress to kidney failure compared to those with lower protein levels.
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Rationale & Objective: This study describes the epidemiology, characteristics, and clinical outcomes of patients with focal segmental glomerulosclerosis (FSGS)-attributed kidney failure in the US Renal Data System (USRDS) during 2008-2018, and health care resource utilization and costs among those with Medicare-linked data.

Study Design: This was a retrospective cohort study.

Setting & Population: Patients with FSGS-attributed kidney failure in the USRDS were enrolled in the study.

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