Blunt aortic dissection and bilateral internal carotid dissection in the setting of polytrauma: A case report.

Severe polytrauma involving multiple organ systems presents a significant challenge to any trauma center. We present a case of a patient presenting simultaneously with a type B aortic dissection, bilateral internal carotid dissections, a brachiocephalic artery dissection, and a splenic laceration among other injuries. In this patient with both solid organ injury and vascular trauma, we discuss how multidisciplinary collaboration was required to prioritize treatment goals and determine the proper initiation of antiplatelet and anticoagulation therapies.

Emergency Trauma Providers as Equal Partners: From "Proof of Concept" to "Outcome Parity".

Enmeshment of emergency trauma providers (ETPs) into the United States health-care fabric resulted in the establishment of a formalized surgical critical care fellowship and certification for emergency medicine trainees. The aim of this study was to compare trauma outcomes for surgery-trained providers (STPs) and ETPs at our institution, hypothesizing patient outcome equivalency. We performed an institutional review board-exempt institutional registry review (January 1, 2004 to August 1, 2018), comparing 74 STPs and 6 ETPs.

Utility of 4-Factor Prothrombin Complex Concentrate in Trauma and Acute-Care Surgical Patients.

Context: Since 2013, prothrombin complex concentrate (PCCs) have been approved in the United States for the reversal of anticoagulation induced by vitamin K antagonists. However, there has been limited investigation into their use in trauma and acute-care surgery (ACS).

Objective: To investigate the role that 4-factor PCC may have in reversing anticoagulation in the setting of trauma and ACS.

Modelling of drug penetration into human skin using a multilayer membrane system.

In this article, a new in vitro model system is presented with a multilayer membrane system serving as acceptor. Matrix-stabilized membranes are applied with dodecanol as lipid and collodion as matrix. Using the drug dithranol it was shown that the acceptor system can be varied over a wide range by changing the dodecanol content of the membranes and by addition of the hydrophilic substance propylene glycol to the membranes.