Publications by authors named "C M Barbera"
Background: Bacterial pulmonary superinfections develop in a substantial proportion of mechanically ventilated COVID-19 patients and are associated with prolonged mechanical ventilation requirements and an increased mortality. Albeit recommended, evidence supporting the use of empirical antibiotics at intubation is weak and of low quality. The aim of this study was to elucidate the effect of empirical antibiotics, administered within 24hours of endotracheal intubation, on superinfections, duration of mechanical ventilation, and mortality in mechanically ventilated patients with COVID-19.
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- The article reflects on how the Milan Approach has evolved since the time of its founders, Luigi Boscolo and Gianfranco Cecchin, while emphasizing a humble perspective from current teachers at Via Leopardi.
- It explores the unique aspects of the Milan model, highlighting the ongoing use of key principles like hypothesizing, circularity, and curiosity that were established in the 1980s.
- The focus is on the adaptability of the approach in response to current social and cultural issues, emphasizing a constant state of questioning and progress in clinical work rather than a fixed identity.
Article Synopsis
- The text refers to a correction made to a previously published article.
- The specific article mentioned can be identified by its DOI, which is 10.1055/a-2411-1814.
- Corrections like this are common in academic publishing to address errors or inaccuracies in research.
Background: EUS-guided gastroenterostomy (EUS-GE) is a novel and effective procedure for the management of malignant gastric outlet obstruction (GOO) with more durable results when compared to enteral stenting (ES). However, data comparing EUS-GE to ES in patients already treated with EUS-guided choledocoduodenostomy (EUS-CDS) for distal malignant biliary obstruction (DMBO) are lacking. We aimed to compare outcomes of EUS-GE and ES for the palliation of GOO in this specific population of patients.
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- - The study investigated outcomes of lumen-apposing metal stents (LAMS) placement in patients with surgically altered anatomy (SAA), which is not well-documented in existing literature, involving 270 patients across 25 tertiary care centers up to November 2023.
- - Technical success of the procedures was very high at 98%, with clinical success at 97%, although there was a notable adverse event rate of 12%, with various degrees of severity recorded.
- - The results suggest that while LAMS placement in SAA is effective, due to the risk of complications, these procedures should only be performed by experienced endoscopists in specialized centers.