Publications by authors named "C Lugo-Candelas"

Article Synopsis
  • - Disruptive behavior disorders (DBDs), which include conduct disorder and oppositional defiant disorder, often overlap with ADHD, but there is a significant difference in their treatment and societal perceptions, pointing to a need for better diagnostic understanding.
  • - Previous smaller studies have hinted at racial disparities in DBD diagnoses as compared to ADHD, prompting a larger investigation into these disparities using a comprehensive dataset of pediatric inpatients.
  • - The study found that certain racial groups, including Native American, Asian, Black, and Hispanic children, were more likely to be diagnosed with DBDs when presenting symptoms similar to those of ADHD, highlighting important questions regarding race and mental health diagnoses.
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Article Synopsis
  • The COVID-19 pandemic has adversely affected the mental health of many individuals, particularly birthing and postpartum women, as they faced significant changes in their daily lives and access to care.
  • A study in Puerto Rico involving 47 mothers showed that depression and anxiety levels significantly increased from the period of March 2020 to April 2021 (T1) compared to May 2022 to May 2023 (T2).
  • Despite some mothers indicating they no longer view the pandemic as a major stressor, feelings of loneliness, sadness, and worry persist, suggesting the need for further exploration of factors affecting maternal mental health during the perinatal period.
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Prenatal depression, a common pregnancy-related risk with a prevalence of 10-20 %, may affect in utero development and socioemotional and neurodevelopmental outcomes in the next generation. Although there is a growing body of work that suggests prenatal depression has an independent and long-lasting effect on offspring outcomes, important questions remain, and findings often do not converge. The present review examines work carried out in the last decade, with an emphasis on studies focusing on mechanisms and leveraging innovative technologies and study designs to fill in gaps in research.

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Background: Prenatal fish intake is a key source of omega-3 (ω-3) polyunsaturated fatty acids needed for brain development, yet intake is generally low, and studies addressing associations with autism spectrum disorder (ASD) and related traits are lacking.

Objective: This study aimed to examine associations of prenatal fish intake and ω-3 supplement use with both autism diagnosis and broader autism-related traits.

Methods: Participants were drawn from 32 cohorts in the Environmental influences on Child Health Outcomes Cohort Consortium.

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This study examined the association between prenatal cannabis exposure and autism spectrum disorder (ASD) diagnoses and traits. A total sample of 11,570 children (ages 1-18; 53% male; 25% Hispanic; 60% White) from 34 cohorts of the National Institutes of Health-funded environmental influences on child health outcomes consortium were included in analyses. Results from generalized linear mixed models replicated previous studies showing that associations between prenatal cannabis exposure and ASD traits in children are not significant when controlling for relevant covariates, particularly tobacco exposure.

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