Characteristics of patients with undiagnosed stage 3 chronic kidney disease: results from an observational study (REVEAL-CKD) in China.

Background: Early diagnosis of chronic kidney disease (CKD) is crucial for timely intervention to delay disease progression and improve patient outcomes. However, data for clinical characteristics of Chinese patients with undiagnosed, early-stage CKD are lacking.

Methods: REVEAL-CKD is a multinational, observational study using real-world data in selected countries to describe factors associated with undiagnosed stage 3 CKD, time to diagnosis, and CKD management post diagnosis.

Enhancing the performance of polyfarnesene-based bio-rubbers with surface-modified cellulose nanocrystals and nanofibers.

As the rubber industry seeks sustainable alternatives to mitigate its environmental impact, this study introduces a biobased approach using polyfarnesene rubber reinforced with plasma-modified cellulose nanocrystals (MCNC) and nanofibers (MCNF). The nanocellulose was modified by plasma-induced polymerization using trans-β-farnesene and was characterized by FTIR, XPS, XRD, TGA, and SEM to confirm the grafting of farnesene-derived polymer chains onto the cellulose surface, demonstrating the successful modification and integration of the nanoparticles. Polyfarnesene bio-based rubbers were synthesized through two different polymerization techniques: solution-based coordination polymerization (PFA1) and emulsion-based free radical polymerization (PFA2).

Racism and Postpartum Blood Pressure in a Multiethnic Prospective Cohort.

Background: Postpartum hypertension is a key factor in racial-ethnic inequities in maternal mortality. Emerging evidence suggests that experiences of racism, both structural and interpersonal, may contribute to disparities. We examined associations between gendered racial microaggressions (GRMs) during obstetric care with postpartum blood pressure (BP).

A Review of Orthodontic Considerations before and after Alveolar Bone Grafting in Patients with Cleft Lip and Palate.

There are many factors to consider regarding the orthodontic treatment of an individual with cleft lip and palate in relation to the alveolar bone graft procedure. Some of these are: the sequence and timing of treatment, indications for pre-graft orthodontics, the appropriate appliances that should be used, and considerations in post-graft orthodontics. A review of some of the current concepts, management, and protocols are described.

Host-microbe computational proteomic landscape in oral cancer revealed key functional and metabolic pathways between Fusobacterium nucleatum and cancer progression.

Oral squamous cell carcinoma (OSCC) is the most common manifestation of oral cancer. It has been proposed that periodontal pathogens contribute to OSCC progression, mainly by their virulence factors. However, the main periodontal pathogen and its mechanism to modulate OSCC cells remains not fully understood.