Publications by authors named "C Lopez-Sanz"
ATAK Complex Induced by Ranitidine: A Comprehensive Concept for Cardiac Involvement in Allergic Reactions.
J Investig Allergol Clin Immunol
November 2024
Article Synopsis
- Allergic diseases, starting early in life, create a chronic inflammatory environment that is linked to metabolic disorders and cardiovascular risks, but the exact mechanisms are still unclear.
- Researchers conducted experiments using a mouse model and various methods to study how allergic inflammation impacts lipid metabolism, specifically focusing on triglyceride levels and gene expression related to fat metabolism.
- The findings indicate that allergic inflammation leads to a specific lipid profile and increased triglycerides in the blood, primarily driven by IgG-mediated responses rather than traditional T-cell reactions.
Article Synopsis
- The study investigates the connection between SARS-CoV-2 viral load (viremia) and genetic variations (SNPs) linked to the severity of COVID-19 in a group of hospitalized patients at University Hospital La Princesa.
- Out of 340 patients analyzed, only 37.1% had positive viremia, with specific SNPs (like rs2071746 and rs78958998) associated with a higher risk of viremia, while others (like rs11052877 and rs33980500) were linked to a lower risk.
- The findings suggest that certain genetic variants contribute to differences in SARS-CoV-2 viremia among individuals, highlighting the