Drug re-challenges in cutaneous adverse drug reactions: information and effectiveness in the long-term management of patients.

Background: In patients with cutaneous adverse drug reactions (CADR), drug skin tests and re-challenge under hospital surveillance (RCH) are helpful. The aim of this study was to determine if patients with negative drug RCH can tolerate subsequent treatments with the same drugs.

Patients And Methods: Patients with a negative RCH in the last 10 years answered a telephone questionnaire which was delivered by the same investigator in order to determine if subsequently the patients were able to tolerate the drug with which they had a negative RCH and also to study the reasons why the drugs were not taken again.

Impact of predialysis therapeutic practices on patient outcomes during the first year of dialysis: the Pharmacoepidemiologic AVENIR study.

Background: Studies evaluating patient outcomes in dialysis as a function of quality of predialysis therapeutic care are lacking.

Objective: To evaluate the association of quality of predialysis therapeutic practices with survival and hospitalization during the first year of dialysis.

Research Design: The AVantagE de la Néphroprotection dans l'Insuffisance Rénale study was an observational cohort study.

[Workload during hemodialysis sessions].

In recent years, the population of dialysis patients has become frailer and older. Patients present with more comorbid conditions and experience more complications during their follow-up. The aim of the present study is to describe the workload of the dialysis center during hemodialysis sessions and determine whether comorbidities are associated with increased workload.

[Interventions implemented to control an outbreak of vancomycin-resistant enterococci in a university hospital].

At the end of 2004, a Vancomycin-resistant enterococci (VRE) outbreak occurred in the university hospital of Nancy. Interventions were simultaneous implemented in this hospital (promotion of hand washing, gathering of VRE carriers in the same part of units) and the outbreak seemed to be controlled before the end of 2005. But one year later, the number of discovered new colonisations increased again.

[Incidence of chronic kidney disease in general population, EPIRAN study].

Aims: To assess incidence of chronic kidney disease in general population and to describe baseline characteristics of incident patients.

Methods: Between 1st/01/04 and 30/06/06 all incident cases of chronic kidney disease in the Nancy district were prospectively identified. New cases were identified from all medical laboratories in this area and determined by a persistently increased serum creatinine level (> or = 150micromol/l, or paediatric levels) for 3 months after the 1st/01/04, and by living in Nancy area.