Publications by authors named "C Lofqvist"
Aim: To analyse the challenges faced by parents of extremely preterm infants born before 24 weeks of gestation and the potential buffering effect of perceived resources on the family's health continuum.
Methods: The qualitative data were obtained from 70 parents of 70 infants born before 24 weeks of gestation, through open-ended questions in a survey. An inductive content analysis was conducted to identify themes and patterns in the parents' experiences.
Article Synopsis
- Neurodevelopmental impairments are prevalent in extremely preterm male infants, potentially linked to increased activity in the hypothalamic-pituitary-gonadal (HPG) axis, though this has been under-researched.
- A study measured levels of testosterone and dihydrotestosterone (DHT) in 25 cord blood samples and 13 postnatal plasma samples from infant males over 11 weeks, revealing initial high levels that quickly declined but remained above expected in utero levels.
- The findings indicate that the HPG axis is activated at birth, leading to an earlier androgen surge than typical, suggesting the need for further research on its long-term effects on neurodevelopment.
Article Synopsis
- This study explores how neurofilament light chain (NfL), a marker for brain injury, relates to neurovascular issues in extremely preterm infants, specifically those born before 28 weeks gestational age.
- Researchers found that higher NfL levels in the first month after birth are associated with severe intraventricular hemorrhage (IVH) and retinopathy of prematurity (ROP), especially in infants born before 25 weeks gestational age.
- The results suggest that NfL could be a potential predictor of neonatal morbidities linked to a more porous blood-brain barrier, indicating the need for further research in this area.
Topic: Retinopathy of prematurity (ROP) is a severe retinal vascular disorder affecting preterm infants, potentially leading to retinal detachment and blindness. This review aims to elucidate the relationship between systemic VEGF levels and ROP.
Clinical Relevance: This systematic review aims to consolidate evidence from available studies to guide future research and inform clinical practice.
Aim: To assess experience of care, well-being of parents and children's development in a cohort of extremely premature infants born <24 weeks of gestation in Sweden from 2007 to 2018.
Methods: A survey based on multiple questionnaires answered by 124/349 (35.5%) parents.