Publications by authors named "C Lo Barco"
Personalized cardiovascular risk assessment in Rheumatoid Arthritis patients using circulating molecular profiles and their modulation by TNFi, IL6Ri, and JAKinibs.
Biomed Pharmacother
April 2024
Article Synopsis
- The study investigated the inflammatory profiles of Rheumatoid Arthritis (RA) patients to identify those at higher risk for cardiovascular (CV) issues and evaluated the effects of specific medications.
- Researchers analyzed data from 387 RA patients, dividing them into groups based on prior CV events and treatment with disease-modifying drugs, while examining various inflammatory biomarkers.
- Findings revealed three distinct RA patient groups with varying inflammatory levels and CV risks, highlighting that certain treatments effectively lowered disease activity and improved inflammatory markers associated with CV risk, suggesting a pathway for personalized management in RA care.
Benign prostatic enlargement (BPE) and big prostates are common. Photovaporization of the prostate (PVP) with Greenlight™ laser 180 W XPS is considered a reliable therapy for prostates <80 mL and an alternative for the treatment of bigger ones in selected cases. The aim of this study is to evaluate efficacy, safety, and functional outcomes of PVP among patients with prostates over and under 80 mL.
View Article and Find Full Text PDFRisks of Adverse Childhood Outcomes According to Prenatal Time of Exposure to Zika Virus: Assessment in a Cohort Exposed to Zika During an Outbreak in Colombia.
J Pediatric Infect Dis Soc
April 2021
Late gestational exposure to Zika increases the odds of delay in the Bayley-II mental developmental index (MDI) in children with normal baseline neurologic assessments; 9-fold when comparing third and first trimester exposure. Risk of MDI developmental delay increases by 8% for each week of gestational age at time of exposure.
View Article and Find Full Text PDFObjective: To describe oncological and functional outcomes in patients treated with reconstructive organ-sparing surgery (OSS) for squamous cell carcinoma of the penis. Plastic reconstructive OSS of the penis with a split thickness skin graft has been proposed as a treatment option for penile cancer, with the objective being preservation of physiological voiding and sexual function without comprising oncological control.
Materials And Methods: Multicenter study reporting clinicopathological data of 57 patients with malignant lesions of the penis treated with OSS and plastic reconstructive surgery with split thickness skin graft from 2007 to 2019.
Background: Despite increasing information in the literature regarding congenital Zika infection, gaps remain in our knowledge of its clinical manifestations.
Methods: We did a prospective observational study of exposed fetuses and infants whose mothers developed symptomatic and confirmed Zika infection during pregnancy in Valle del Cauca, Colombia. We performed neurological, ophthalmologic and audiologic evaluations, and classified outcomes as possibly or uncertainly related to Zika.