Publications by authors named "C Linhart"
Background: Fragility fractures of the pelvis (FFP) in elderly patients are an increasing concern due to their association with osteoporosis and the aging population. These fractures significantly affect patients' mobility and quality of life. This study evaluates different surgical techniques in patients suffering from FFP to provide standardized recommendations for treatment strategies.
View Article and Find Full Text PDF: The surgical management of periprosthetic femoral fractures is particularly challenging in geriatric patients due to physiological limitations. The choice between open reduction and internal fixation (ORIF) and hip revision arthroplasty for treating Vancouver B2 and B3 fractures remains controversial. This study aims to contribute further evidence by analyzing the in-hospital outcomes in geriatric patients with Vancouver B2/3 fractures.
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- The study aimed to assess the accuracy of a fully automated AI solution for interpreting HER2 immunohistochemistry (IHC) in breast cancer, acknowledging the need for more reliable HER2 scoring due to the effectiveness of HER2-targeted therapies.
- In a two-arm study involving 120 HER2 IHC whole-slide images and four surgical pathologists, the AI solution showed improved interobserver agreement and scoring accuracy compared to manual readings, particularly for distinguishing between HER2 0 and 1+ cases.
- The results indicate that the AI tool can enhance the consistency and reproducibility of HER2 scoring, supporting pathologists in following ASCO/CAP guidelines more effectively.
Background: Fiji is a Pacific Island nation with the predominant ethnic groups indigenous Fijians (iTaukei) (62 %) and Fijians of Indian descent (31 %). This study reports on the effect of a Parental Assistance Payment Program (PAPP) tied to on-time birth registration, available in Fiji from August 2018 to July 2020.
Methods: Unit record birth registration data ( = 117,829) for children born during 2016-22 were used to calculate mean birth-to-registration intervals and the likelihood of on-time birth registration (within 365 days) before the PAPP (January 2016-July 2018) compared to during the PAPP (August 2018-July 2020), by population disaggregations (sex, ethnicity, age, marital status).