Publications by authors named "C Lettieri"

Trigeminal neuralgia is a neuropathic pain syndrome responsive to botulinum toxin type A therapy. This review had the goal of analyzing the different studies published from 2002 to January 2024 to better define the techniques and the types of botulinum toxin type A used, the doses, the injection routes, and the different populations of trigeminal neuralgia patients treated. We considered only articles in which the therapy was administered to humans to treat trigeminal neuralgia.

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Aims: The aim of this study is to assess the sleep quality and daytime sleepiness improvement in chronic migraineurs after 6 months of a 2:1 KD (ketogenic diet) and LGID (low-glycemic-index diet).

Methods: Twenty-six patients underwent 2:1 KD (11 patients) and LGID (15 patients). PSQI (Pittsburgh sleep quality index) and ESS (Epworth sleepiness scale) were administered at the baseline and the 3-month and 6-month follow-up.

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Article Synopsis
  • Current guidelines recommend keeping LDL-C levels below 55 mg/100 ml for patients with acute coronary syndromes (ACS), but many patients struggle to reach this target due to poor medication adherence.
  • A study analyzed 963 ACS patients, using the Morisky Medication Adherence Scale to categorize them into high adherence (HA) and low adherence (LA) groups, finding that 28.7% had low adherence.
  • The results showed that HA patients were significantly more likely to achieve the LDL-C target compared to LA patients, indicating that adherence to lipid-lowering therapy plays a crucial role in reaching cholesterol goals.
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Objective: We monitored cognition in 14 Parkinson's disease (PD) patients during deep brain stimulation (DBS) surgery when the electrode was positioned at the target subthalamic nucleus (STN) (i.e., the STN motor area).

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  • The study investigates the differences in clinical features and spread risk of oromandibular dystonia (OMD) between idiopathic and acquired subtypes, based on a retrospective analysis of 273 patients from the Italian Dystonia Registry.
  • It was found that idiopathic cases mainly exhibited sensory tricks and a family history, with a notable 34% of focal OMD patients experiencing spread within the first five years.
  • The research highlights a potential link between sensory tricks and OMD spread, suggesting estrogen's role in dystonia development and providing a basis for further studies on underlying mechanisms and treatment options.
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