Publications by authors named "C Lersch"
Background: Platelets are major players of thrombosis and inflammation after acute myocardial infarction (AMI). The impact of thrombocytopenia on platelet-induced cellular processes post AMI is not well defined.
Methods: The left anterior descending artery was ligated in C57/Bl6 mice and in two thrombocytopenic mouse models to induce AMI.
Background: The use of knock-out mouse models is crucial to understand platelet activation and aggregation.
Methods: Analysis of the global double fluorescent Cre reporter mouse that has been crossbred with the megakaryocyte/platelet specific mouse.
Results: Platelets show bright ( negative) and ( positive) fluorescence.
Background: Reasons for and frequency of nonadherence to antiretroviral therapy (ART) may have changed due to pharmacological improvements. In addition, the importance of known non-pharmacologic reasons for nonadherence is unclear.
Methods: We performed a cross-sectional, noninterventional, multicenter study to identify current reasons for nonadherence.
Background/objectives: According to the widely accepted "Cambridge Classification", one of the morphological criteria for chronic pancreatitis (CP) is enlargement of the pancreas. Increased size seems to be an obvious feature of an inflammatory disease. However, it has never been validated so far, if CP is indeed accompanied by significant enlargement of the pancreas.
View Article and Find Full Text PDFPurpose: Time savings and clinical accuracy of a new miniature ultrasound device was investigated utilizing comparison with conventional high-end ultrasound instruments. Our objective was to determine appropriate usage and limitations of this diagnostic tool in internal medicine.
Methods: We investigated 28 patients from the internal-medicine department.