Publications by authors named "C Leclercq"
Background: Following implantation/replacement of an implantable cardioverter-defibrillator, patients are legally subjected to variable lengths of driving restrictions based on the indication (1 and 3 months after primary and secondary prevention, respectively; 1 week after device replacement).
Aim: To assess the incidence of ventricular arrhythmia during the theoretical driving restriction period in a large cohort of patients.
Methods: Patients who underwent implantable cardioverter-defibrillator implantation for primary or secondary prevention or device replacement between 2015 and 2021 were included retrospectively.
Epidemiology of major heart rhythm and conduction disorders.
Arch Cardiovasc Dis
December 2024
Article Synopsis
- Heart rhythm and conduction disorders vary in severity and can be benign or life-threatening, with a focus on their epidemiology in France.
- A study analyzed hospitalization data from 2022 and mortality from 2021 to assess the prevalence of three main conditions: atrial fibrillation/flutter, conduction disorders, and ventricular tachycardia/cardiac arrest.
- Findings revealed over 2.7 million individuals impacted by these disorders as of January 2023, with significant hospitalization rates and a concerning 44% mortality rate for those hospitalized due to ventricular tachycardia/cardiac arrest.
Atrial fibrillation (AF) is the primary cause of ischaemic stroke and transient ischaemic attack (TIA). AF is associated with a high risk of recurrence, which can be reduced using optimal prevention strategies, mainly anticoagulant therapy. The availability of effective prophylaxis justifies the need for a significant, coordinated and thorough transdisciplinary effort to screen for AF associated with stroke.
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- The study introduces a new technique called multielectrode catheter-induced ectopy mapping (MECIE mapping) to help locate the origins of infrequent premature ventricular complexes (PVCs) for effective ablation treatment.
- Researchers enrolled 29 patients with infrequent PVCs and used MECIE mapping to create a detailed local activation time map, achieving high concordance with the clinical PVCs.
- After an average follow-up of about 13 months, 93.1% of the patients experienced an 80% or greater reduction in PVCs, indicating that MECIE mapping is a promising strategy for successful PVC ablation.
Article Synopsis
- Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening syndrome that can occur in individuals with genetic predispositions or in immunocompromised patients, though it’s particularly rare in solid organ transplant recipients, such as lung transplant patients.
- This case study presents an unusual incident of HLH developing 11 years after lung transplantation in a 67-year-old patient, with symptoms including pancytopenia, fever, and splenomegaly, and showed signs of post-transplant lymphoproliferative disorder (PTLD).
- Despite treatment with etoposide, corticosteroids, and rituximab, the patient ultimately died from complications, highlighting the need for