Publications by authors named "C Le Roux-Villet"

Introduction: Although the treatment for pemphigus vulgaris (PV) has been revolutionized by the use of rituximab combined with corticosteroids, new effective therapies with a better safety profile are needed.

Observation: A 67-year-old woman was diagnosed with severe mucosal PV, which was initially misdiagnosed as atypical Behçet's disease. Following an unsuccessful colchicine treatment, significant improvement was observed upon the introduction of apremilast: reduced pain, fewer lesions, and a stabilized weight.

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Article Synopsis
  • Lichen planus pemphigoides (LPP) is a rare autoimmune disease that causes blisters and can affect mucous membranes, though this aspect has not been thoroughly studied before.* -
  • The study analyzed 12 cases of LPP primarily involving mucous membranes, confirming the diagnosis through specific histological and immunological tests.* -
  • Treatment typically involves corticosteroids, which work better in cases with skin involvement; however, for those with significant mucous membrane issues, immunomodulators may be more effective as an initial treatment.*
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