Publications by authors named "C Lamirel"

We present a method for mapping multifocal Pupillary Response Fields in a short amount of time using a visual stimulus covering 40° of the visual angle divided into nine contiguous sectors simultaneously modulated in luminance at specific, incommensurate, temporal frequencies. We test this multifocal Pupillary Frequency Tagging (mPFT) approach with young healthy participants (N = 36) and show that the spectral power of the sustained pupillary response elicited by 45 s of fixation of this multipartite stimulus reflects the relative contribution of each sector/frequency to the overall pupillary response. We further analyze the phase lag for each temporal frequency as well as several global features related to pupil state.

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Introduction: Even though the local tolerance of prostaglandin (PG) analogues has improved drastically since the introduction of preservative-free (PF) eye drops, prescription patterns still vary widely among practitioners and between countries and could have an impact on the ocular surface of treated patients and, in consequence, their adherence. The aim of this study is to explore the prescribing patterns of PG analogues monotherapy in France and to evaluate their impact on ocular surface status.

Methods: This was a national multicenter cross-sectional observational study that was conducted by 18 glaucoma experts in France.

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Article Synopsis
  • Optic nerve head edema (ONHE) is commonly found in patients with optic neuritis (ON) and its connection to MRI abnormalities is not well understood, prompting this study to examine how effectively T2 FLAIR MRI can identify ONHE in acute ON cases.
  • This study analyzed data from 102 patients with acute ON and found a high agreement (92%) between MRI findings and fundus photography, indicating that MRI can reliably detect ONHE.
  • The research concluded that T2 FLAIR MRI is a sensitive and specific method for diagnosing ONHE, which can aid in the assessment of patients with optic neuritis.
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Article Synopsis
  • Previous studies on acute optic neuritis (ON) often had equal patient groups, which doesn't reflect real-life occurrences, leaving it unclear what features effectively differentiate ON causes.
  • This study evaluated adult patients with recent acute ON to determine if clinical assessments, CSF analysis, and MRI imaging can help differentiate ON causes in a practical setting.
  • Results showed that factors like bilateral visual involvement and specific CSF and MRI findings were key in identifying ON types, while traditional eye tests showed no significant differences.
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Prcis: Global peripapillary retinal nerve fiber layer thickness (pRNFL)/Bruch membrane opening-minimum rim width (BMO-MRW) ratio is an objective and effective parameter to separate glaucomatous optic neuropathies (GONs) from nonGONs (NGONs).

Purpose: This study was undertaken to evaluate the diagnostic capability of the pRNFL/ BMO-MRW ratio to differentiate GONs from NGONs.

Patients And Methods: This retrospective study included patients with an optic neuropathy (ON), visual loss for>6 months and a confirmed single etiology.

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