Publications by authors named "C Lahoz"
Article Synopsis
- Recent research highlights the glymphatic system's role in neurodegeneration, leading to the development of a new analysis method called DTI-ALPS for assessing brain health.
- This study conducts a Bayesian meta-analysis on 12 Parkinson's and 11 Alzheimer's studies to evaluate the reliability of DTI-ALPS across different research, aiming to differentiate between these disorders.
- Findings indicate that DTI-ALPS consistently reflects the glymphatic system's health in both diseases and could serve as a valuable tool in diagnosing and understanding neurodegenerative conditions.
Background: To our knowledge, only one study has examined the association between glucose variability (GV) and mortality in the elderly population with diabetes. GV was assessed by HbA1c, and a J-shaped curve was observed in the relationship between HbA1c thresholds and mortality. No study of GV was conducted during the COVID-19 pandemic and its lockdown.
View Article and Find Full Text PDFThe irruption of lipoprotein(a) (Lp(a)) in the study of cardiovascular risk factors is perhaps, together with the discovery and use of proprotein convertase subtilisin/kexin type 9 (iPCSK9) inhibitor drugs, the greatest novelty in the field for decades. Lp(a) concentration (especially very high levels) has an undeniable association with certain cardiovascular complications, such as atherosclerotic vascular disease (AVD) and aortic stenosis. However, there are several current limitations to both establishing epidemiological associations and specific pharmacological treatment.
View Article and Find Full Text PDFOne of the objectives of the Spanish Society of Arteriosclerosis is to contribute to the knowledge, prevention and treatment of vascular diseases, which are the leading cause of death in Spain and entail a high degree of disability and health expenditure. Atherosclerosis is a multifactorial disease and its prevention requires a global approach that takes into account the associated risk factors. This document summarises the current evidence and includes recommendations for patients with established vascular disease or at high vascular risk: it reviews the symptoms and signs to evaluate, the laboratory and imaging procedures to request routinely or in special situations, and includes the estimation of vascular risk, diagnostic criteria for entities that are vascular risk factors, and general and specific recommendations for their treatment.
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