Publications by authors named "C Lagneau"

Article Synopsis
  • Researchers developed a SAR (Structure-Activity Relationship) model to help identify new mosquito repellents from a dataset of 2,171 molecules, using detailed molecular descriptors as inputs.
  • The best-performing model, a three-layer perceptron with a structure of 20/6/2, achieved 94% accuracy on training data and 89% on test data.
  • This model was further utilized to predict the repellent effectiveness of new molecules, with two of them successfully tested in live organisms.
View Article and Find Full Text PDF

Urban Aedes mosquitoes are vectors of many viruses affecting human health such as dengue, chikungunya and Zika viruses. Insecticide resistance and environmental toxicity risks hamper the effectiveness of chemical control against these mosquito vectors. Alternative control methods, such as the use of mosquito-specific entomopathogenic viruses should be explored.

View Article and Find Full Text PDF

Aedes albopictus, also known as the "Asian Tiger Mosquito", is an invasive mosquito species to Europe causing high concern in public health due to its severe nuisance and its vectorial capacity for pathogens such as dengue, chikungunya, yellow fever and Zika. Consequently, the responsible authorities implement management activities to reduce its population density, possibly to below noxious and epidemiological thresholds. In urban areas, these aims are difficult to achieve because of the species' ability to develop in a wide range of artificial breeding sites, mainly private properties.

View Article and Find Full Text PDF

Space spraying of deltamethrin allows the control of adult Aedes (Stegomyia) aegypti mosquitoes. Unfortunately, many vector control programs are threatened by the development of resistances that decrease the efficacy of this adulticide. Faced with this situation, we can either try to use another insecticide presenting a different mechanism of action or find a strategy that brings back the efficacy of the insecticide at a satisfying level to pursue its use in vector control.

View Article and Find Full Text PDF

Background: Ultra-low volume (ULV) insecticidal aerosols dispensed from vehicle-mounted cold-foggers are widely considered the method of choice for control of Aedes aegypti and Ae. albopictus during outbreaks of dengue and chikungunya and, more recently, Zika. Nevertheless, their effectiveness has been poorly studied, particularly in Europe.

View Article and Find Full Text PDF