Cytopathology of glioneuronal and neuronal tumours with histological correlations.

Glioneuronal and neuronal tumours constitute a diverse group of tumours that feature neuronal differentiation. In mixed glioneuronal tumours, a glial component is present in addition to the neuronal component. With a few exceptions (eg diffuse leptomeningeal glioneuronal tumour) they are well-circumscribed and slow-growing tumours, which is why their prognosis is intrinsically favourable after gross total resection.

Intraoperative consultation on pediatric central nervous system tumors by squash cytology.

Squash cytology (SC) is a very useful procedure during neurosurgical intraoperative consultation (IOC), and it is especially recommended for the evaluation of soft tumors or tumors that are highly cellular (just the characteristics of pediatric central nervous system [CNS] tumors). The aim of this review is to familiarize pathologists with the range of cytomorphologic appearances that can occur during IOC for pediatric CNS tumors and with the diagnostic dilemmas and pitfalls encountered in this setting. This article is based on the medical literature and the authors' experience with a large series of cases accrued over a 12-year period at 3 institutions.

Astroglial cell subtypes in the cerebella of normal adults, elderly adults, and patients with Alzheimer's disease: a histological and immunohistochemical comparison.

Objectives and experimental design Cerebella of young adults, elderly adults, and patients with Alzheimer's disease (AD) (with and without cerebellar amyloid deposits) were studied by Golgi staining and glial fibrillary acid protein (GFAP) immunocytochemical methods. Observations Three subtypes of Golgi epithelial cells and nine subtypes of stellate neuroglia (both normal and hypertrophic) were defined by their morphology, their GFAP-reactivity, their specific location in the cortical layers, and their responses in senility and AD. The GFAP immunoreaction was subtype specific.

[Heart failure patients in Primary Care: aging, comorbidities and polypharmacy].

Objective: To assess heart failure prevalence, epidemiology, co-morbidities and polypharmacy in our region from electronic patient records. To evaluate gender differences in heart failure patients.

Design: Descriptive, cross-sectional study.

Calretinin-immunopositive cells and fibers in the cerebellar cortex of normal sheep.

Calretinin (CR)-immunopositive cells and fibers in the cerebellar cortex (vermal archicerebellum--lobules X and IX--and neocerebellum--lobules VIIb and VIII) of two and 4-year-old Manchega and Rasa Aragonesa sheep were studied. CR-immunoreactivity was seen in subsets of all neurons and afferent fibers described in the cerebellar cortex. Generally, immunopositive cells were seen in very high densities in lobules X and IX, and in low density in lobule VIIb.