Publications by authors named "C Labbe"

Black aluminum is a material characterized by high surface porosity due to columnar growth and exhibits unique optical properties that make it attractive for applications such as light trapping, infrared detection, and passive thermal radiation cooling. In this study, we correlate the structural and optical properties of black aluminum by comparing it with conventional reflective aluminum layers. These layers of varying thicknesses were deposited on fused silica substrates, and their optical properties were analyzed.

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Introduction: Consolidation durvalumab post chemo-radiotherapy (CRT) has been demonstrated to improve survival in locally advanced non-small-cell lung cancer (NSCLC). Real-world data to assess its use and impact on patients, particularly in Quebec, remain limited.

Methods: We, therefore, aimed to assess real-world durvalumab use in inoperable stage III NSCLC in Quebec, to describe progression-free survival (PFS) and overall survival (OS) outcomes as reported in the PACIFIC trial, and to evaluate safety and toxicity.

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Article Synopsis
  • Research culture in health and biomedical sciences is heavily shaped by academic pressures like the need to publish, impacting the quality of evidence produced.
  • This rapid scoping review aims to identify various factors affecting research culture by analyzing empirical studies from PubMed and Web of Science published between 2012 and April 2024.
  • The findings highlight the importance of inclusivity, transparency, rigor, and objectivity in research practices, suggesting that ongoing discussions about these principles are essential for improving research environments.
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Spermatogonia cryopreservation is a method to preserve valuable genomes from both maternal and paternal origin. The damage associated with the application of this technology on post-thaw cell quality is important to assess, including at the epigenetic level. This study aimed to assess post-thawed spermatogonia quality by evaluating alterations in plasma membrane integrity, DNA integrity (fragmentation and apoptosis), lipid peroxidation (malondialdehyde levels) and epigenetic modifications (DNA methylation profile).

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Article Synopsis
  • * The IND.242 trial aims to assess the effectiveness of JDQ443 (opnurasib), a selective KRAS G12C inhibitor, in improving major pathological response rates in patients with resectable NSCLC.
  • * This trial involves 27 patients and includes objectives related to safety, response rates, event-free survival, and exploring biomarkers that could predict treatment outcomes.
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