Identification of genetic loci and candidate genes underlying Fusarium crown rot resistance in wheat.

A major locus Qfcr.cau-1B conferring resistance to Fusarium crown rot was identified and validated. The putative gene underlying this locus was pinpointed via virus-induced gene silencing.

Unraveling Spatial Heterogeneity in Mass Spectrometry Imaging Data with GraphMSI.

Mass spectrometry imaging (MSI) provides valuable insights into metabolic heterogeneity by capturing in situ molecular profiles within organisms. One challenge of MSI heterogeneity analysis is performing an objective segmentation to differentiate the biological tissue into distinct regions with unique characteristics. However, current methods struggle due to the insufficient incorporation of biological context and high computational demand.

Diagnostic and therapeutic role of non-coding RNAs regulating programmed cell death in melanoma.

lncRNAs (long non-coding RNAs) are heterogeneous RNA molecules that modulate various cellular processes, such as proliferation, differentiation, migration, invasion, and apoptosis, via different mechanisms. An increasing amount of research indicates that abnormal expression of lncRNA influences the development of drug resistance as well as the genesis and advancement of cancer, including melanoma. Furthermore, they are attractive biomarkers for non-invasive cancer diagnostics due to their strongly modulated expression and improved tissue and disease specificity.

Study of Water Resistance of Polyurethane Coatings Based on Microanalytical Methods.

This study investigates the effect of microstructural changes in polyurethane coatings on their water resistance properties. Polyurethane coatings with varying diluent contents were prepared and tested for water penetration resistance and mechanical property retention. The time-dependent behavior of water within the coatings at different immersion durations was analyzed using low-field nuclear magnetic resonance (NMR).

Fabricating a SFMA/BAChol/PAA/ZnCl Hydrogel with Excellent Versatile Comprehensive Properties and Stable Sensitive Freezing-Tolerant Conductivity for Wearable Sensors.

Flexible wearable sensors have obtained tremendous interest in various fields and conductive hydrogels are a promising candidate. Nevertheless, the insufficient mechanical properties, the low electrical conductivity and sensitivity, and the limited functional properties prevent the development of hydrogels as wearable sensors. In this study, an SFMA/BAChol/PAA/ZnCl hydrogel was fabricated with high mechanical strength and versatile comprehensive properties.