Publications by authors named "C L Winder"

Introduction: Access to veterinary services is integral for animals of all species. These services play a crucial role in maintaining their health and welfare and maintaining a healthy, safe, and sustainable food system. Research has consistently shown that rural communities face challenges accessing veterinary services, with livestock producers outlining several barriers including cost, inadequate infrastructure, and delays in receiving treatments.

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The objective of this randomized clinical trial was to assess whether early intervention with a nonsteroidal anti-inflammatory drug (NSAID) following a disease alert generated by automated milk feeders could reduce diarrhea severity and improve performance in dairy calves. Seventy-one Holstein calves were enrolled on an automated milk feeder (recorded milk intake and drinking speed) at 3 d of age and received up to 15 L/d (150 g/L) of milk replacer until 35 d of age. An alert that was previously validated as diagnostically accurate to identify calves at risk for diarrhea was used using automated milk feeder data (≤60% rolling dividends in milk intake and/or drinking speed over 2 d).

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Objectives: The burden of acute gastrointestinal illness (AGI) attributable to natural water recreation in Canada is unknown. Understanding the burden can help prioritize public health interventions and resource allocation for reduction of disease. Our objectives were to compile estimates of AGI burden associated with natural water recreation, identify knowledge gaps in water recreation epidemiology, and evaluate methods applicable for developing a burden estimate for Canada.

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Objectives: The burden of disease associated with acute gastrointestinal illness (AGI) in Canada is estimated to be ~ 20 million cases/year. One known risk factor for developing AGI is recreation in freshwater bodies such as lakes. The proportion of cases attributable to freshwater recreation in Canada, however, is currently unknown.

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Molecularly imprinted polymers (MIPs) are a class of synthetic recognition materials that offer a cost-effective and robust alternative to antibodies. While MIPs have found predominant use in biosensing and diagnostic applications, their potential for alternative uses, such as enzyme inhibition, remains unexplored. In this work, we synthesized a range of acrylamide-based hydrogel MIP microparticles (35 μm) specific for the recognition of α-amylase.

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