Bionomics and distribution of malaria vectors in Kisumu city, Western Kenya: implications for urban malaria transmission.

Background: Increasing unplanned urbanization in tropical Africa may create new niches for malaria vectors, raising transmission risk, yet control efforts focus on rural ecosystems. Understanding mosquito diversity, ecology and biting behaviour in urban areas is crucial for effective control. This study assessed Anopheles diversity, abundance, behaviour, and Plasmodium infection rates in Kisumu city, Kenya.

Transcriptomic and metabolomic analysis reveal the cold tolerance mechanism of common beans under cold stress.

Background: Common bean (Phaseolus vulgaris L.) is a thermophilic crop, and exposure to cold stress can significantly impact their yield and quality. To elucidate the impact of cold stress on cold-tolerant 'Wei Yuan' (WY) and cold-sensitive 'Bai Bu Lao' (BBL) of common bean, the mechanism of cold tolerance was studied by physiological and biochemical and multi-omics analysis.

The comparative efficacy of L-glutamine, celecoxib, and glucosamine sulfate in osteoarthritis management.

To explore the therapeutic efficacy of L-glutamine (L-Gln) on pathological progression and clinical symptoms of osteoarthritis (OA), and compare with glucosamine sulfate (GS), and celecoxib (CXB). Rats were administered sodium chloride, L-Gln, GS, or CXB via gavage for eight weeks starting from the fifth week after sham operation or Anterior Cruciate Ligament Transection (ACLT) + Medial Meniscectomy (MMx). Then the severity of knee OA in rats was evaluated by serological analysis, histological examination and imaging examination.

Embedding polydopamine in keratin-based biohydrogels for efficient dye removal.

Keratin-based hydrogels have shown promise as materials for wastewater remediation, yet their low surface area and poor mechanical performance hindered the practical application. To address these challenges, we developed a bowl-shaped polydopamine-loaded sponge bio-hydrogel (BPSH) with a hierarchical porous structure and high stability. The extruded keratin chains facilitated the formation of three distinct macroporous frameworks, while embedding bowl-shaped polydopamine into the bio-hydrogel significantly enhanced the hierarchical porous structure.