Publications by authors named "C L Walters"
Objective: We aim to evaluate the quality of patient-reported outcomes included in randomized control trials for the treatment of congestive heart failure using the International Society for Quality of Life Research (ISOQOL) checklist, a validated tool for critically appraising the quality of patient-reported outcomes.
Design: We performed a cross-sectional analysis of 65 randomized control trials with patient-reported outcomes for drug intervention trials for treating congestive heart failure.
Setting: N/A.
Article Synopsis
- A study in Australia explored the experiences of family carers supporting individuals with mental health issues during the COVID-19 pandemic, highlighting increased anxiety and distress due to service disruptions.
- Researchers used a 71-question online survey to gather data on family carers' experiences, revealing that they often supported multiple people, resulting in increased caregiving hours and complex challenges.
- The findings suggest that government policies during the pandemic did not adequately address the financial, practical, or emotional needs of family carers, potentially leading to negative mental health outcomes for them.
Memory formation is contingent on molecular and structural changes in neurons in response to learning stimuli-a process known as neuronal plasticity. The initiation step of mRNA translation is a gatekeeper of long-term memory by controlling the production of plasticity-related proteins in the brain. The mechanistic target of rapamycin complex 1 (mTORC1) controls mRNA translation, mainly through phosphorylation of the eukaryotic initiation factor 4E (eIF4E)-binding proteins (4E-BPs) and ribosomal protein S6 kinases (S6Ks).
View Article and Find Full Text PDFIntroduction: In the United States, maternal mortality is high and patterned by race and socioeconomic status (SES). Patient-provider relationships and societal discrimination have been separately associated with poor maternal outcomes, but it is not clear how such mechanisms may be interrelated. Thus, the present study investigates how societal experiences of discrimination are associated with and manifest in patient-provider relationship quality among perinatal women.
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- The study investigates the effectiveness and costs of two types of external fixator clamps—standard and multipin—used for treating high-energy tibia fractures while minimizing complications.
- A review of 100 patients treated from 2014 to 2023 showed no significant differences in clinical outcomes or radiographic alignment between the two types of external fixators, despite the multipin clamps being more expensive.
- The findings suggest that the choice of clamp may not impact treatment results, leading to considerations for cost-effectiveness in clinical practice.