Publications by authors named "C L Tsien"
Objective: Recent U.S. registry publications showed no improvement in long-term survival post-liver transplant in the last three decades.
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- Many liver transplantation programs no longer require a set period of abstinence for candidates, but effective monitoring for ongoing alcohol use is necessary.
- Urinary ethyl glucuronide (EtG) testing is highlighted as an objective measure to detect alcohol consumption in patients with alcohol-associated liver disease (ALD) during the pretransplant phase.
- In a study of 497 ALD patients, only 8% tested positive for EtG, with severe alcohol use disorder, lower daily consumption, and prolonged substance use being significant factors linked to positive results; psychiatric issues were not strongly related.
Introduction: Frailty is a recognized condition associated with poorer outcomes in patients with head and neck cancer (HNC). The objective of this study was to ascertain the prognostic significance of various frailty metrics on short-term treatment toxicity in patients with HNC undergoing curative-intent therapy.
Materials And Methods: A systematic review was performed searching multiple databases.
Aim: To investigate the efficacy and safety of glucagon-like peptide-1 receptor agonists (GLP-1RAs) and sodium-glucose cotransporter-2 (SGLT2) inhibitors in liver transplant (LT) recipients with diabetes.
Methods: A single-centre, retrospective analysis of prospectively collected data from an LT recipient database (1990-2023) was conducted. We included adults with pre-existing diabetes and post-transplant diabetes, newly started on GLP-1RAs and/or SGLT2 inhibitors after LT.