Diagnosis of systemic or visceral candidosis.

Although systemic or visceral candidosis can be diagnosed during life, it is usually discovered at autopsy. Early diagnosis is important since treatment with specific antifungal drugs is effective. The diagnosis should rest on all available clinical and laboratory evidence.

Efficiency of serologic tests in the diagnosis of systemic candidiasis.

Candida antibody tests for systemic candidiasis were conducted on 53 sera from patients with the disease and 170 sera from control patients by agar gel diffusion, counterimmunoelectrophoresis (CIE), latex agglutination, and whole-cell agglutination. The agar gel diffusion test and CIE had sensitivity, specificity, and efficiency of approximately 90%. The whole-cell agglutination test scored significantly lower, whereas the latex test scored in between.

Advances in the diagnosis of renal candidiasis.

Candiduria may signify benign saprophytic colonization or true infection of the urinary tract. Histological studies of 64 suspect cases of renal candidiasis, 20 of them positive, suggest that a Candida colony count of 10,000 to 15,000 per ml. or more in a catheterized specimen is a useful cut-off point between infection and colonization.