Publications by authors named "C L Marsh"

Purpose: We hypothesized that male and female volunteers would exhibit distinct changes in cardiac morphology, systolic, and diastolic function following endurance (END) and resistance (RES) training.

Methods: Thirty-eight females and 26 males participated in a randomized cross-over design trial in which all participants completed 12-weeks END and RES, separated by a 12-week washout. Echocardiograms assessed morphology (left ventricular mass, LVM), systolic function (ejection fraction, EF, and global longitudinal strain, GLS), diastolic function (mitral valve velocities, E, A; tissue Doppler velocities, e', a'), and left atrial volume.

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The impacts of degradation and deforestation on tropical forests are poorly understood, particularly at landscape scales. We present an extensive ecosystem analysis of the impacts of logging and conversion of tropical forest to oil palm from a large-scale study in Borneo, synthesizing responses from 82 variables categorized into four ecological levels spanning a broad suite of ecosystem properties: (i) structure and environment, (ii) species traits, (iii) biodiversity, and (iv) ecosystem functions. Responses were highly heterogeneous and often complex and nonlinear.

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  • Inflammasomes are important protein complexes in the immune system, and their malfunction is connected to various health issues, necessitating targeted treatments based on specific diseases.
  • Researchers developed a sophisticated imaging assay for human immune cells, utilizing machine learning and cell biology techniques to analyze cellular responses related to inflammasome activity.
  • This approach successfully identified over 100 distinct inflammasome inhibitors from a large library of compounds, showcasing the potential for machine learning to enhance the understanding of complex biological processes and aid in drug discovery.
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  • * Focus groups conducted with 19 women revealed that many had never heard of PrEP but showed a strong desire to learn more, highlighting barriers such as partner negotiation, adherence, and misconceptions about HIV.
  • * Participants expressed high trust in family planning center providers and suggested that community outreach and tailored strategies are essential for improving PrEP uptake among these women.
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Hydrologic reconstructions from North America are largely unknown for the Middle Miocene. Examination of fungal palynomorph assemblages coupled with traditional plant-based palynology permits delineation of local, as opposed to regional, climate signals and provides a baseline for study of ancient fungas. Here, the Fungi in a Warmer World project presents paleoecology and paleoclimatology of 351 fungal morphotypes from 3 sites in the United States: the Clarkia Konservat-Lagerstätte site (Idaho), the Alum Bluff site (Florida), and the Bouie River site (Mississippi).

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