Publications by authors named "C L Mallucci"
Purpose: This study presents a series of paediatric meningiomas and discusses aetiology, risk factors and outcomes with comparison to current literature.
Methods: This is a retrospective review of surgically treated paediatric meningiomas from three UK centres: the University Hospital of Wales, Alder Hey Children's Hospital and Royal Manchester Children's Hospital. Twenty-seven patients aged 16 and under at the time of their first procedure were identified over a 15-year period (1 January 2007 and 1 March 2023).
Article Synopsis
- Comprehensive reporting of clinical trial activity is essential, guided by the SPIRIT 2013 and CONSORT 2010 statements, which outline what should be included in protocols and result articles.
- A review analyzed the reporting quality of 9 trial protocols and 76 trial result articles related to pediatric brain tumors, revealing an average adherence of 76.8% for protocols and around 67-71% for result articles to established reporting standards.
- The findings suggest a need for improved reporting quality in pediatric neuro-oncology, especially regarding randomization and blinding, echoing similar issues previously identified in adult trials.
Purpose: Pediatric low-grade gliomas (pLGG) are the most common brain tumors in children and achieving complete resection (CR) in pLGG is the most important prognostic factor. There are multiple intraoperative tools to optimize the extent of resection (EOR). This article investigates and discusses the role of intraoperative ultrasound (iUS) and intraoperative magnetic resonance imaging (iMRI) in the surgical treatment of pLGG.
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- * A study analyzing 39 adult patients with TPGs from 1993 to 2021 found that about 20% experienced tumor progression over a median follow-up of 10 years, with a high overall survival rate of 86.5%.
- * The study highlights the importance of identifying risk factors for TPG progression and suggests that future research should focus on larger cohorts for more definitive conclusions about long-term outcomes.
Purpose: Posterior fossa tumour surgery in children entails a high risk for severe speech and language impairments, but few studies have investigated the effect of the tumour on language prior to surgery. The current crosslinguistic study addresses this gap. We investigated the prevalence of preoperative word-finding difficulties, examined associations with medical and demographic characteristics, and analysed lexical errors.
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