Publications by authors named "C L Leach"
Aims: To examine the predictability of categorical and quantitative study variables on acute stroke knowledge amongst study participants.
Design: Non-experimental, descriptive correlational.
Methods: A convenience sample of registered nurses caring for adult, hospitalized patients recruited from the urban Southeast.
Structural inequities impede technology uptake in marginalized populations living with type 1 diabetes (T1D). Our objective was to describe hemoglobin A1c (HbA), time in range (TIR), and pump use to evaluate the impact of a universal funding policy for continuous glucose monitoring (CGM) across levels of deprivation in children with T1D in the Canadian province of British Columbia (BC). Patients with T1D and at least one outpatient visit after June 10, 2020 (1-year before universal CGM funding) who were enrolled in the BC Pediatric Diabetes Registry were included ( = 477).
View Article and Find Full Text PDFBackground: Proprioception is an essential sensory function of the body. Proprioception is defined as one's awareness of their body's position and movement through space. It contributes to both the conscious and unconscious awareness of limb and trunk position and movement.
View Article and Find Full Text PDFArticle Synopsis
- * Conducted across 24 sites in ten countries, 1200 cancer patients on opioid analgesics completed questionnaires assessing their constipation status, revealing that 59.5% met the criteria for OIC, but only 61.5% self-reported experiencing constipation.
- * Results indicated that while 72% were prescribed laxatives or other treatments, only 66% consistently used them, leading to inadequate management of OIC due to poor assessment and treatment follow-up.
Article Synopsis
- Research is focused on finding new biologically active compounds, specifically Azothioformamides (ATFs), which can form stable coordination complexes with metals like copper for potential anticancer and antimicrobial therapies.
- In this study, different ATF ligands with varying heterocyclic groups were synthesized and complexed with Cu(I) salts, which were chosen for their potential lower toxicity and effective binding properties.
- The results indicated that smaller pyrrolidine-substituted ATFs showed stronger binding to Cu(I) salts and had varying levels of antimicrobial activity, particularly against some cancer cell lines, while the ATF ligands alone showed limited effectiveness.