Publications by authors named "C L Kempton"

Background: Therapeutic plasma exchange (TPE) is the primary intervention for treating symptomatic hyperviscosity from hypergammaglobulinemia, yet its efficacy for treating hyperviscosity related to hyperfibrinogenemia is unclear.

Objective: Define the safety and efficacy of TPE for critically ill COVID-19 patients with elevated blood viscosity from hyperfibrinogenemia.

Method: A prospective, randomized controlled trial in critically ill COVID-19 patients at a single US healthcare system.

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Introduction: The needs of haemophilia carriers (HC) have been historically overlooked. It is now recognised that HC manifests bleeding symptoms, including haemarthrosis. The natural history of joint health in HC is not yet defined.

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Article Synopsis
  • Women and girls are rarely included in clinical trials for haemophilia.
  • There is a need for specific strategies to intentionally recruit more female participants in these trials.
  • Enhancing inclusivity in haemophilia research will lead to better understanding and treatment options for women and girls with the condition.*
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Introduction: Both men and women can be diagnosed with haemophilia and the experience with haemophilia may be different between men and women.

Aim: This study aimed to compare patient-reported outcomes in men versus women with haemophilia.

Methods: This cross-sectional study is a post-hoc analysis of data collected as part of the Haemophilia-related Distress Questionnaire validation study.

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