Publications by authors named "C L Karras"

Background And Objective: While safe and effective modalities exist to treat small arteriovenous malformations (AVMs), large (>10 cm) AVMs remain difficult to cure via surgical or endovascular means. Staged stereotactic radiosurgery (SRS), either volume-staged (VS) or dose-staged (DS), has been proposed for large AVMs. The relative efficacy of these two strategies, with or without endovascular embolization, is unclear.

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Objective: To preserve facial nerve function in vestibular schwannoma (VS) microsurgery, some have advocated subtotal resection (STR) if the tumor is densely adherent to a thinned facial nerve. The objective of this study was to determine if residual volume is associated with progression and whether there is a threshold residual volume that should be pursued during STR to prevent recurrence. A secondary objective of this study was to determine whether facial nerve function at last follow-up was associated with extent of resection (EOR).

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Objective: Cervical spinal cord injury (SCI) and lower trunk brachial plexus injury (BPI) commonly result in hand paralysis. Although restoring hand function is complex and challenging to achieve, regaining volitional hand control drastically enhances functionality for these patients. The authors aimed to systematically review the outcomes of hand-opening function after supinator to posterior interosseous nerve (PIN) transfer.

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Article Synopsis
  • The study investigates the clinical characteristics and outcomes of trigeminal schwannoma (TS) surgical resections across two institutions from 2004 to 2022, analyzing data from 30 patients.
  • Most patients were middle-aged, with common symptoms including sensory loss and headaches; tumors primarily consisted of mixed cystic-solid types with an average diameter of 3.3 cm.
  • Although 87% of patients reported symptom improvements after surgery, there were notable risks, with 17% experiencing temporary and 10% experiencing permanent cranial nerve deficits.
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