Publications by authors named "C L Guma"

Article Synopsis
  • - Antimicrobial resistance (AMR) is a significant public health issue in Uganda, highlighted by a study that analyzed data from 10 tertiary hospitals between October 2020 and March 2023, revealing varying levels of resistance among different patient demographics and specimen types.
  • - Among the 2754 isolates collected, common pathogens included common strains with only a small percentage being susceptible to key antibiotics like ceftriaxone (28%) and methicillin (44% susceptibility, with 56% identified as MRSA).
  • - The study found trends in susceptibility changes over time, revealing significant decreases in effectiveness of ciprofloxacin and gentamicin, indicating a pressing need for improved antimicrobial stewardship to combat AMR drivers.
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Article Synopsis
  • * The rise of antibiotic resistance, although a natural phenomenon, is increasingly influenced by human activity, and if not managed, could jeopardize recent medical and agricultural advancements.
  • * The article discusses Uganda's efforts in developing an antimicrobial resistance surveillance strategy as part of its National Action Plan, demonstrating progress in tracking and analyzing antibiotic resistance trends.
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Objective.  The aim of our work was to investigate whether lateral stimulation of the spinal cord, lateral cord stimulation (LCS), results in inhibition of the spastic phenomena of upper motor lesions in an animal model. Methods.

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Objective.  Classically, a decerebrated animal by mesencephalic lesioning is considered the paradigm for experimental study of spasticity that accompanies cerebral palsy, but, the model does not actually correspond with anatomical and pathologic realities. Therefore, a new and novel animal model is needed.

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