Converting Fe-N-C single-atom catalyst to a new FeNxSey cluster catalyst for proton-exchange membrane fuel cells.

Fe-N-C catalyst is the most promising alternative to platinum catalyst for proton-exchange membrane fuel cells (PEMFCs), however its high performance cannot be maintained for a long enough time in device. The construction of a new Fe coordination environment that is different from the square-planar Fe-N 4 configuration in Fe-N-C catalyst is expected to break current stability limits, which however remains unexplored. Here, we report the conversion of Fe-N-C to a new FeNxSey catalyst, where the Fe sites are three-dimensionally (3D) co-coordinated by N and Se atoms.

Therapeutic dose prediction using score-based diffusion model for pretreatment patient-specific quality assurance.

Objectives: Implementing pre-treatment patient-specific quality assurance (prePSQA) for cancer patients is a necessary but time-consuming task, imposing a significant workload on medical physicists. Currently, the prediction methods used for prePSQA fall under the category of supervised learning, limiting their generalization ability and resulting in poor performance on new data. In the context of this work, the limitation of traditional supervised models was broken by proposing a conditional generation method utilizing unsupervised diffusion model.

Proteomic analysis of spinal dorsal horn in prior exercise protection against neuropathic pain.

Neuropathic pain (NP) is a complex and prevalent chronic pain condition that affects millions of individuals worldwide. Previous studies have shown that prior exercise protects against NP caused by nerve injury. However, the underlying mechanisms of this protective effect remain to be uncovered.

Identification of Potential Intervention Targets Involved in Prior Exercise that Attenuates Peripheral Neuropathic Pain by Integrating Transcriptome and Whole-genome Bisulfite Sequencing Analyses.

Changes in DNA methylation and subsequent alterations in gene expression have opened a new direction in research related to the pathogenesis of peripheral neuropathic pain (PNP). This study aimed to reveal epigenetic perturbations underlying DNA methylation in the dorsal root ganglion (DRG) of rats with peripheral nerve injury in response to prior exercise and identify potential target genes involved. Male Sprague-Dawley rats were divided into three groups, namely, chronic constriction injury (CCI) of the sciatic nerve, CCI with prior 6-week swimming training (CCI_Ex), and sham operated (Sham).

Korean Gastric Cancer Association-Led Nationwide Survey on Surgically Treated Gastric Cancers in 2023.

Purpose: Since 1995, the Korean Gastric Cancer Association (KGCA) has been periodically conducting nationwide surveys on patients with surgically treated gastric cancer. This study details the results of the survey conducted in 2023.

Materials And Methods: The survey was conducted from March to December 2024 using a standardized case report form.