Background And Objective: The purpose of this study was to develop a feedback control system for the pulsed holmium:YAG medical laser that enhances tissue selectivity and safety by discriminating between soft and hard biological tissue such as urinary and biliary calculi and bone.
Study Design/materials And Methods: The ability to discriminate is achieved by monitoring prompt laser-induced visible/NIR photoemissions via retrograde transmission over the laser delivery fiber in conjunction with a developed detection algorithm.
Results: Experimental data are presented for a system that employs this discrimination scheme with an electro-optic shutter for rapid intrapulse feedback control of holmium laser-based lithotripsy procedures.