Publications by authors named "C L Fletcher"

Background: In recent years, Europe has experienced several outbreaks of West Nile Virus (WNV), a mosquito-borne pathogen. This study aims to quantify the impact of weekly mean temperature and cumulative precipitation on human cases of West Nile Neuroinvasive Disease (WNND), to assess the feasibility of climate-informed early warning systems for severe forms of WNV infection.

Methods: Using a space-time-stratified case-crossover design, the short-term effects of meteorological factors on WNND cases reported in Europe from 2014 to 2022 were examined.

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Article Synopsis
  • - A genome assembly was created from a female Shoulder-striped Wainscot moth, covering 751.70 megabases and organized into 32 chromosomal pseudomolecules, including sex chromosomes Z and W.
  • - The assembly includes a mitochondrial genome that measures 15.37 kilobases.
  • - Gene annotation through Ensembl revealed a total of 12,477 protein-coding genes in this genome.
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We present a genome assembly from an individual male (the Common Wainscot moth; Arthropoda; Insecta; Lepidoptera; Noctuidae). The genome sequence has a total length of 719.10 megabases.

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Article Synopsis
  • ChILD is a group of rare and severe lung diseases in children, with some cases linked to deficiencies in surfactant protein B (SP-B).
  • The RespiRare network helps to gather detailed information about the characteristics and genetic backgrounds of these patients.
  • A study involving 11 patients found that those with complete SP-B deficiency showed symptoms at birth and had a median survival of 1 month, while rarer cases with partial SP-B function might have a better chance of survival.
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