Enantio-Recognition and Charge Transfer Complex Formation Involving Tetrathiafulvalene-Appended Chiral 1,2-Cyclohexane-Diamine: An Integrated Experimental and Theoretical Study.

In this work, we exploit the electronic features of tetrathiafulvalene (TTF) as a backbone in synthesizing chiral derivatives. The aim is to make use of TTF's well-known and unique redox and semiconducting properties in the fields of enantio-selective recognition and chiral charge transfer (CT) complex preparation, with the ultimate objective of obtaining devices with various potential applications, ranging from plasmonics to quantum computing. In particular, both cyclohexane-bis (TTF-amide)-based enantiomers 1-(S,S) and 1-(R,R), stable under an oxidation regime, have been selected, and under these conditions, the electrochemical enantiospecific response of the four possible systems, coming from the combination with L- and D-tartaric acid, respectively, was tested.

ATTRACTOR-BASED MODELS FOR SEQUENCES AND PATTERN GENERATION IN NEURAL CIRCUITS.

Neural circuits in the brain perform a variety of essential functions, including input classification, pattern completion, and the generation of rhythms and oscillations that support processes such as breathing and locomotion [51]. There is also substantial evidence that the brain encodes memories and processes information via of neural activity. In this dissertation, we are focused on the general problem of how neural circuits encode rhythmic activity, as in central pattern generators (CPGs), as well as the encoding of sequences.

Stable fixed points of combinatorial threshold-linear networks.

Combinatorial threshold-linear networks (CTLNs) are a special class of recurrent neural networks whose dynamics are tightly controlled by an underlying directed graph. Recurrent networks have long been used as models for associative memory and pattern completion, with stable fixed points playing the role of stored memory patterns in the network. In prior work, we showed that of the graph correspond to stable fixed points of the dynamics, and we conjectured that these are the only stable fixed points possible [1, 2].

Primary headache with onset in childhood and adolescence: natural history and prognostic factors in a Portuguese population.

Introduction: Headaches are the most frequent neurological disorder in the pediatric population, with great impact on quality of life. This study aims to characterize a cohort of patients followed at a pediatric neurology unit between January 1st 2013 and December 31st, 2021.

Materials And Methods: We reviewed medical records and selected patients with primary headaches and a minimum follow-up of 12 months.