Publications by authors named "C L Cook"
Background: Cardiovascular disease (CVD) is a leading cause of death in ANCA-associated vasculitis (AAV). Screening and primary cardiovascular prevention may improve outcomes.
Methods: We identified patients in the 2002-2019 Mass General Brigham AAV cohort with thoracic CT scans obtained for other clinical purposes.
Background And Aims: Guidelines suggest non-traumatic out-of-hospital cardiac arrest (OHCA) be conveyed to cardiac arrest centres (CAC). We hypothesised that (a) a pre-hospital conveyance algorithm based on initial presenting rhythm following OHCA is feasible and (b) that would demonstrate survival advantage.
Methods: This observational pilot study included all consecutive patients with OHCA from suspected cardiac aetiology from the county of Essex, United Kingdom from April 2022-April 2023.
Introduction: Transcatheter aortic valve replacement (TAVR) is increasingly in demand for treating severe aortic stenosis in a variety of surgical risk profiles. This means increasing wait times and elevated morbidity and mortality on the waitlist. To address this, we developed the SWIFT TAVR algorithm to prioritize patients based on clinical risk and reduce wait times.
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- Single crystals of organic compounds that respond to heat or light are well-studied, but those showing extreme mechanical response are less common in research.
- A tetrafluoro(aryl)sulfanylated bicyclopentane developed in this study exhibited a low-temperature thermosalient effect, where crystals jumped and disintegrated at temperatures below ∼193 K.
- Investigations using various techniques revealed that the mechanical response is not solely due to a chemical transformation or phase transition, but rather related to the release of built-up strain and possibly influenced by microstructural changes or impurities within the crystal.
Article Synopsis
- Rugby training and competition create varying levels of training load (TL) that impact athlete well-being, but the relationship between TL and well-being is not fully understood.
- During a 3-week study with 22 elite male rugby players, researchers assessed TL and well-being indicators like mood and fatigue multiple times a week.
- Results showed that higher daily TLs correlated with negative changes in well-being, including decreases in mood and sleep quality, and increases in stress and fatigue, with effects varying over time based on the TL experienced.
- Understanding this relationship can help coaches and athletes develop better training and recovery strategies to enhance performance and well-being.