Alterations in newborn metabolite patterns with preterm birth and diabetes in pregnancy.

Background: This study examines the influence of prematurity and diabetes (DM) in pregnancy on metabolite patterns at birth, and associations with adiposity development in a prospective cohort.

Methods: Term and preterm (30-36 weeks gestational age [GA]) infants were enrolled and body composition assessments completed through discharge. Targeted metabolomics was used to assess metabolites in cord or infant blood in the first 2 days.

The impact of brain-systemic oxygenation coupling in sleep-disordered breathing on cognitive function in elderly.

Background: Intermittent hypoxia, a consequence of sleep-disordered breathing (SDB), may contribute to an increased risk of cognitive decline. However, the association between SDB and cognition remains highly variable.

Methods: Fifty-two community-dwelling healthy older adults (28 women) were recruited.

Heterologous immunization strategy developed broadly reactive human monoclonal antibodies against the BK virus.

BK polyomavirus (BKV) causes polyomavirus-associated nephropathy (PyVAN) and polyomavirus-associated hemorrhagic cystitis (PyVHC) following kidney transplantation and allogeneic hematopoietic stem cell transplantation (HST). BKV strains fall into four distinct genotypes (BKV-I, -II, -III, and -IV) with more than 80% of individuals are seropositive against BKV-I genotype, while the seroprevalence of the other four genotypes is lower. PyVAN and PyVHC occurs in immunosuppressed (e.

Final CONUS Results on Coherent Elastic Neutrino-Nucleus Scattering at the Brokdorf Reactor.

The CONUS experiment studies coherent elastic neutrino-nucleus scattering in four 1 kg germanium spectrometers. Low ionization energy thresholds of 210 eV were achieved. The detectors were operated inside an optimized shield at the Brokdorf nuclear power plant which provided a reactor antineutrino flux of up to 2.

Challenges of regional hospice and palliative care networks: A group discussion study with coordinators and network experts.

Background: Within hospice and palliative care, professionals from various disciplines collaborate to deliver comprehensive care to terminal patients and their relatives. Regional hospice and palliative care networks exist in various countries, aimed at facilitating cooperation among health care providers at a local level. To date, little is known about the challenges faced by these networks.