Publications by authors named "C L Boulton"

Article Synopsis
  • Coccidioidomycosis is a fungal infection common in the southwestern U.S. that can affect the musculoskeletal system, particularly in serious cases, though lower extremity involvement is less frequently documented.
  • The study highlighted three cases from southern Arizona showcasing different manifestations of lower extremity osteoarticular coccidioidomycosis, each with distinct clinical challenges and treatment approaches.
  • Effective treatment typically involves surgical debridement and extended antifungal therapy, emphasizing the need for careful diagnosis as the symptoms often resemble non-infectious conditions.
View Article and Find Full Text PDF

Neoantigen immunogenicity prediction is a highly challenging problem in the development of personalised medicines. Low reactivity rates in called neoantigens result in a difficult prediction scenario with limited training datasets. Here we describe ImmugenX, a modular protein language modelling approach to immunogenicity prediction for CD8+ reactive epitopes.

View Article and Find Full Text PDF

Objective: The objective of our study was to assess the impact of heat stress on hydration and cognition among outdoor workers in hot environment.

Methods: Area heat stress assessments were measured using Quest Temp WBGT monitor. Sweat rate for dehydration and reaction time for acute cognitive processing were recorded using standard procedures.

View Article and Find Full Text PDF