Publications by authors named "C L Benvenuti"

Article Synopsis
  • CDK4/6 inhibitors have greatly improved treatment for hormone receptor-positive breast cancer, but developing resistance to these drugs remains a significant issue with few guidelines for alternative treatments.
  • Continuing CDK4/6 inhibition, possibly alongside endocrine therapy or new drugs, is an active area of research that may change treatment practices based on the results of ongoing clinical trials.
  • Evidence suggests switching to a different CDK4/6 inhibitor after progression can have limited benefits, and current biomarker analyses for patient selection have been inconsistent, indicating that further research and validation are necessary before making this approach standard practice.
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Background: Predicting the incidence of time-sensitive cardiovascular diseases like out-of-hospital cardiac arrest (OHCA), ST-elevation myocardial infarction (STEMI), and stroke can reduce time to treatment and improve outcomes. This study analysed the spatio-temporal distribution of OHCAs, STEMIs, and strokes, their spatio-temporal correlation, and the performance of different prediction algorithms.

Methods: Adults who experienced an OHCA, STEMI, or stroke in Canton Ticino, Switzerland from 2005 to 2022 were included.

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Modern healthcare is experiencing a significant transformation, utilizing technology to improve patient outcomes and make processes more efficient. Breast cancer, being the most commonly diagnosed cancer in women globally, requires innovative approaches for effective management. Digital Therapeutics (DTx) and Clinical Decision Support Systems (CDSSs) have emerged as pivotal technologies, offering personalized, patient-centered care and optimizing clinical decision-making.

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Background: Popillia japonica Newman is a scarab beetle native to Japan that is considered a serious pest outside its native range. It can feed on more than 400 host plants and spread about 10 km per year in invaded territories, therefore it is considered the second most important quarantine pest in Europe. Both chemical and biological insecticides have been used for control, with variable results.

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The treatment of early triple-negative breast cancer (eTNBC) has improved patients' prognosis but often leads to adverse events and sequelae affecting quality of life (QoL). Pain Neuroscience Education (PNE) is a promising non-pharmacological intervention in this field. Preliminary data have shown the beneficial effect of PNE in BC survivors.

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