Publications by authors named "C L'Acqua"
Article Synopsis
- * A total of 614 patients from nine studies were analyzed, showing the score's ability to predict in-hospital mortality with an area under the curve (AUC) of 0.678 and for V-A-ECMO mortality with an AUC of 0.652, both statistically significant.
- * Results indicate that the PC-ECMO score can be an effective tool for assessing patient risk in clinical settings, making it useful for future research and potential treatment strategies.
Article Synopsis
- Patients undergoing postcardiotomy V-A-ECMO have a high risk of early mortality, with a 66.7% in-hospital mortality rate found in the analysis of 1269 patients across 25 hospitals.
- The study utilized a systematic review and methods like propensity score matching to identify performance differences among hospitals, revealing that some hospitals had significantly higher mortality rates than others.
- The research indicates that lower annual volumes of V-A-ECMO procedures may lead to worse outcomes, and it highlights the potential for improvement in many hospitals' results for this treatment.
Article Synopsis
- Postcardiotomy veno-arterial extracorporeal membrane oxygenation (V-A-ECMO) has a high mortality rate, and determining which patients are at the greatest risk for death is challenging, making clinical judgment essential for initiating the procedure.
- A systematic review analyzed data from 1269 patients across 10 studies, revealing that higher arterial lactate levels at the start of V-A-ECMO correlate with increased in-hospital mortality rates and a significant cut-off level of 6.8 mmol/L for predicting outcomes.
- The findings suggest that monitoring arterial lactate levels may aid clinicians in making more informed decisions on when to start V-A-ECMO, especially in older patients with elevated lactate levels.
Background: It is unclear whether peripheral arterial cannulation is superior to central arterial cannulation for postcardiotomy veno-arterial extracorporeal membrane oxygenation (VA-ECMO).
Methods: A systematic review was conducted using PubMed, Scopus, and Google Scholar to identify studies on postcardiotomy VA-ECMO for the present individual patient data (IPD) meta-analysis. Analysis was performed according to the intention-to-treat principle.