Publications by authors named "C Kumarappan"
Article Synopsis
- The study investigates the prevalence of adverse drug reactions (ADRs) among pharmacists in the Asir area of Saudi Arabia and their knowledge of ADR reporting systems.
- A survey involving 97 pharmacists shows that while 78.4% are aware of the ADR reporting system, only 56.7% recognize the Saudi FDA as the regulatory body, and 73.2% cite workplace stress as a major barrier to reporting.
- The findings highlight that although pharmacists have knowledge of ADR reporting, they generally have negative attitudes towards it, suggesting a need for enhanced training and awareness initiatives.
Understanding the genetic aspects of resistance to antidepressants treatment.
Eur Rev Med Pharmacol Sci
July 2020
Major depression disorder (MDD) is an extremely prevalent disorder and is expected to be the second leading cause of disease burden by 2020 according to the World Health Organisation (WHO). Moreover, this disease burden is predicted to rise in the next 20 years. Antidepressant medications are vital in the therapy of major depression.
View Article and Find Full Text PDFPolyphenol extract of ichnocarpus frutescens leaves modifies hyperglycemia in dexamethasone (dex) treated rats.
Indian J Physiol Pharmacol
August 2015
Introduction: The leaves of Ichnocarpus frutescens are used extensively as a decoction for the treatment of diabetes mellitus by the tribals of Karnataka and Uttar Pradesh states.
Methods: Anti-diabetic activity of polyphenol extract of Ichnocarpus frutescens was investigated using dexamethasone (DEX) induced hyperglycemia in Wistar rats. Experimental animals were injected subcutaneously with dexamethasone 3 mg/kg/day.
Many medicinal plants have been used for centuries in daily life to treat microbial diseases all over the world. In this study, the in vitro antibacterial activity of aqueous and ethanol root extracts of Thespesia populnea Linn were investigated. Antimicrobial properties of T.
View Article and Find Full Text PDFIn the present study antioxidant activities by (1,1-diphenyl-2-picrylhydrazyl radical (DPPH), hydrogen peroxide, hydroxyl radical inhibition, hemolysis by hydrogen peroxide assay, reducing power and total antioxidant activities of polyphenolic extract of Ichnocarpus frutescens leaves were investigated. The flavonoids and total polyphenolic contents of the extract were also determined using standard methods. Phytochemical analyses revealed the presence of flavonoids, polyphenols, anthocyanins and simple phenolic acids.
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