Publications by authors named "C Kors"
Purpose: Since skin is highly accessible, clinical photography is a useful tool to visually substantiate the real-world effectiveness outcomes of biologic-treated adults with moderate-to-severe psoriasis (PsO). We report the effectiveness and patient-reported outcomes at Week 12 between anti-interleukin (IL)-17A biologics and other biologics as well as ixekizumab and guselkumab in patients with available clinical photography at baseline and Week 12.
Patients And Methods: The Psoriasis Study of Health Outcomes (PSoHO) is an international, non-interventional, cohort study investigating the effectiveness of biologics in adults with moderate-to-severe psoriasis at Week 12.
Article Synopsis
- Parainfluenza virus 5 (PIV5) is an enveloped virus with a negative-strand RNA genome, and its replication is regulated by the phosphoprotein (P) interacting with the nucleoprotein (N) and RNA polymerase (L).
- The study reveals the crystal structure of unassembled PIV5 N in complex with a P-derived peptide, highlighting the structural organization of N into N-terminal and C-terminal domains and identifying a key RNA binding site.
- Findings show that the P peptide prevents N oligomerization and maintains N in an open form, crucial for RNA binding and release, which is vital for understanding paramyxovirus replication regulation.
Acne inversa is a chronic inflammatory destructive skin disease that affects about 1% of the population. The therapy should be personalized and consists of surgical and conservative procedures. Antibiotics are administered either topically or systemically.
View Article and Find Full Text PDFBackground And Objectives: Adapalene 0.1 %/benzoyl peroxide (BPO) 2.5 % (Epiduo®) is the first, fixed-dose topical combination gel developed for the once-daily treatment of acne.
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