Publications by authors named "C Koerner-Rettberg"
Article Synopsis
- * Data were collected from 408 PCD patients across 12 countries, focusing on their lung function and the presence of common respiratory pathogens, with a significant finding that those with certain pathogens had lower lung function scores.
- * The results indicated that certain pathogens were strongly associated with decreased lung function, particularly in adults, highlighting the need for early eradication strategies and timely treatment of infections in PCD patients.
Article Synopsis
- Maintaining physical fitness is crucial for adults with cystic fibrosis (pwCF), but there is limited data on how new therapies like ETI affect their fitness levels over time.
- A study tracked 28 adult pwCF for about 5.6 years, measuring various physical fitness components and health indicators like BMI and FEV1, finding significant improvements in BMI and some health-related fitness measures after starting ETI therapy.
- While ETI therapy showed some positive effects, the overall impact on fitness was small, suggesting that other factors also play a role in achieving high physical fitness in pwCF.
Longitudinal changes in habitual physical activity in adult people with cystic fibrosis in the presence or absence of treatment with elexacaftor/tezacaftor/ivacaftor.
Wolfgang Gruber Florian Stehling Christopher Blosch Stefanie Dillenhoefer Margarete Olivier Cordula Koerner-Rettberg
Front Sports Act Living
February 2024
Article Synopsis
- Habitual physical activity and exercise training are crucial for improving health and quality of life in people with cystic fibrosis (pwCF), particularly with the advent of new CFTR modulator therapies like Elexacaftor/Tezacaftor/Ivacaftor (ETI).
- A study was conducted to evaluate the effects of ETI on habitual physical activity, measuring steps per day and intensity among adult pwCF over time, with a focus on data collected during the post-pandemic period.
- Results showed that pwCF on ETI increased daily steps by 25%, while those not receiving ETI saw a slight decline; however, changes in lung function were significant for those on
Purpose: In late 2022, a surge of severe S. pyogenes infections was reported in several European countries. This study assessed hospitalizations and disease severity of community-acquired bacterial infections with S.
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